Clostridioides difficile (C. difficile) remains a major cause of healthcare-associated diarrhoea, with rising antibiotic resistance and frequent relapses making treatment increasingly difficult. While faecal microbiota transplantation has shown promise, the exact mechanisms behind its success remain unclear, highlighting the urgent…
In this study schistosomiasis research is boosted by developing the first controlled human infection model using female-only Schistosoma mansoni parasites. This innovative approach aims to accelerate vaccine development and deepen our understanding of early immune responses to the disease. Thirteen…
Despite decades of effort, malaria remains a global health challenge, with current vaccines offering only modest and short-lived protection. This clinical trial brings fresh hope by testing a next-generation vaccine strategy using live, genetically attenuated Plasmodium falciparum parasites. In this…
Hookworm remains a persistent health threat in many parts of the world, with reinfection common despite mass drug treatments. This study offers insights into how the human immune system responds to hookworm, thus providing crucial knowledge for developing an effective…
